Evelina Children's Hospital, Guy's & St Thomas's Trust
St Thomas’ Hospital
Lambeth Palace Road
London SE1 7EH, UK
Homepage

 

Project leader

 

Dr Eric Rosenthal MD FRCP

Consultant Paediatric & Adult Congenital Cardiologist

Phone: (44) (0)20 7188 4559

Fax:       (44) (0)20 7188 4556

Email: Eric.Rosenthal@gstt.nhs.uk

 

Description of organization

The Evelina Children’s Hospital (ECH) is attached to St Thomas’ Hospital as part of the Guy’s & St Thomas’ NHS Foundation Trust which together manages all aspects of heart disease from fetal life, through infancy and childhood into adult life. Research takes place into physiological, interventional and surgical aspects of heart disease. There is a large cardiac magnetic resonance unit and echocardiography department. The echocardiography department undertakes all currently used clinical techniques and is leading on the development of 3‐dimensional echocardiography. There is a full electrophysiological service with a special interest in the causes of and prevention of sudden death. There is a large paediatric and adult renal unit that undertakes transplantation at all ages. The paediatric unit has extensive experience in the use of 24 hour ambulatory blood pressure monitoring across the paediatric age range in clinical and research settings. The overall research strategy is contained within the recently established King’s Health Partner’s Academic Health Science Centre that includes Kings College London, Kings College Hospital and the South London and Maudsley NHS Foundation Trusts University directed by Professor Robert Lechler. Together these partners care for the largest population of any Academic Health Science Centre in the UK. Our current research plans are focused on both medical science and translational research and the proposed study complies well with the organization’s strategy.

 

Previous experience

We are currently involved with large ongoing projects that involve stratification of echocardiographic techniques and ambulatory blood pressure monitoring across the paediatric population.

 

Profile of staff members

Eric Rosenthal (MD, FRCP) is a paediatric and adult congenital cardiologist with a special interest in electrophysiology. He has received research grants from the British Heart Foundation for basic cardiac research. He has undertaken drug studies and collaborative European and international projects and published over 100 peer‐reviewed papers.

John M Simpson (MD, FRCP) is a fetal and paediatric cardiologist with a special interest in echocardiography. He has received training grants from the British Heart Foundation for echocardiography and leads on the use of 3‐dimensional echocardiography in children with congenital heart disease. He takes part in multi‐centre echocardiographic studies.

Manish Sinha (MB, MRCPCH) is a paediatric nephrologist with a special interest in the investigation and management of hypertension. He has developed techniques to analyze and stratify ambulatory blood pressures in children and adolescents.

 

Main tasks in this project

ECH will analyze and measure the echocardiographic and ambulatory blood pressure parameters for all participating centres in WP3. It will also actively contribute to the patient recruitment in WP3.

News

The fifth ADDUCE Newsletter is now available!

Here, you can read about the finalisation of the project,

the European Medicines Agency and General Assembly meetings

and the dissemination of the results!

The fourth ADDUCE Newsletter is available!
 
In this newsletter, you can find some information on the final recruitment status of the 2 main studies:
- the prospective open-label methylphenidate pharmacovigilance study

- the long-term cardiascular effects of methylphenidate use
 
Also, you can read about the future plans of the project!

More than 1500 children, adolescents and adults across all Europe already took part in our study! Thanks to them, we have already gathered lots of information so we can know a lot more about methylphenidate than ever before! 

 

Did you participate in the ADDUCE studies and are you curious about the latest news on the project?

Here you can find some information!

News for children, April 2015

News for adolescents, April 2015

News for parents, April 2015

The third ADDUCE Newsletter is available!
 

Read more about the ADDUCE studies:

- the prospective open-label methylphenidate pharmacovigilance study: recruitment status and spin-
off studies
- the long-term cardiovascular effects of methylphenidate use: study design and participation
 

and much more in the ADDUCE Newsletter 3, March 2015

 

The second ADDUCE Newsletter is available!
Read more about the 2 main ADDUCE studies:

  • WP3: prospective open-label methylphenidate
    pharmacovigilance study
  • WP8: long-term cardiovascular effects of methylphenidate use

and much more in the ADDUCE Newsletter 2, February 2013

Events

16 - 19 OCTOBER 2016:

4rd EUNETHYDIS International Conference on ADHD, Berlin - Germany
from basis neuroscience to optimised clinical care

17 & 18 APRIL 2016:

ADDUCE Consortium meeting, London - UK

28 - 31 MAY 2015:

5th World Congress on ADHD: from Child to Adult Disorder, Glasgow - Scotland

20 & 21 APRIL 2015:

ADDUCE Consortium meeting, Salina - Italy

21 - 24 MAY 2014:

3rd EUNETHYDIS International Conference on ADHD, Istanbul - Turkey
ADHD and related disorders

19 & 20 MAY 2014:

ADDUCE Consortium meeting, Istanbul - Turkey

3 - 6 OCTOBER 2013:

23rd EUNETHYDIS Network Meeting, Prague Czech Republic
A meeting of the European Network of Hyperkinetic Disorders

6 - 9 JUNE 2013:            

4th World Congress on ADHD: from Childhood to Adult Disease, Milan - Italy

4 & 5 JUNE 2013:

ADDUCE Consortium meeting, Milan - Italy

 6 & 7 JUNE 2012:            

ADDUCE Consortium meeting, Cagliari - Italy

23 MAY 2012:

2nd EUNETHYDIS International Conference on ADHD, Barcelona - Spain